Marek's Disease Virus (MDV) Encodes an Interleukin-8 Homolog (vIL-8): Characterization of the vIL-8 Protein and a vIL-8 Deletion Mutant MDV
نویسندگان
چکیده
منابع مشابه
Structural requirements for gp80 independence of human herpesvirus 8 interleukin-6 (vIL-6) and evidence for gp80 stabilization of gp130 signaling complexes induced by vIL-6.
Human herpesvirus 8 interleukin-6 (vIL-6) displays 25% amino acid identity with human IL-6 (hIL-6) and shares an overall four-helix-bundle structure and gp130-mediated STAT/mitogen-activated protein kinase signaling with its cellular counterpart. However, vIL-6 is distinct in that it can signal through gp130 alone, in the absence of the nonsignaling gp80 alpha-subunit of the IL-6 receptor. To i...
متن کاملIdentification of the Receptor and Cellular Ortholog of the Marek's Disease Virus (MDV) CXC Chemokine
Marek's disease virus (MDV) is a cell associated alphaherpesvirus that causes fatal lymphoma in chickens. One factor that plays a crucial role in MDV pathogenesis is the viral CXC chemokine vIL-8 that was originally named after chicken interleukin 8 (cIL-8). However, a recent study demonstrated that vIL-8 recruits B cells and a subset of T cells but not neutrophils, suggesting that vIL-8 is not...
متن کاملThe VIL (Virtual Immersive Learning) test-bed
The Virtual Immersive Learning (VIL) test-bed implements a virtual collaborative immersive environment, capable of integrating natural contexts and typical gestures, which may occur during traditional lectures, enhanced with advanced experimental sessions. The main aim of the paper is to describe the test-bed motivations, as well as the most significant choices, both hardware and software, adop...
متن کاملInterleukin 8 (IL-8) - a universal biomarker?
Many clinical conditions including various types of cancers are complex and generally require invasive, laborious, expensive and time-consuming investigations for their diagnosis, treatment and follow-up. There is therefore a general need for exploring non-invasive markers in clinical medicine. Interleukin 8 (IL-8) is currently being applied in various subspecialties of medicine either for the ...
متن کاملFrequent Itemsets Mining with VIL - Tree Algorithm
The aim of this paper is to develop a new mining algorithm to mine all frequent itemsets from a transaction database called the vertical index list (VIL) tree algorithm. The main advantages of the previous algorithms, which are frequent pattern (FP) growth and inverted index structure (IIS) mine, are still useful in a new approach as database scanning only done once, and all frequent itemsets a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Virology
سال: 2001
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.75.11.5159-5173.2001